Prognostic and Predictive Value of KRAS Mutation in NSCLC.

Abstract

...we suggest another biological pathway that is associated with EGFR/KRAS signaling.

Liver kinase B1 gene (LKB1), a serine/threonine kinase, is a frequently mutated tumor suppressor gene in NSCLC... Refers to: Alona Zer, Keyue Ding, Siow Ming Lee, Glenwood D. Goss, Lesley Seymour, Peter M. Ellis, Allan Hackshaw, Penelope A. Bradbury, Lei Han, Christopher J. O’Callaghan, Ming-Sound Tsao, Frances A. Shepherd

Pooled Analysis of the Prognostic and Predictive Value of KRAS Mutation Status and Mutation Subtype in Patients with Non–Small Cell Lung Cancer Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Journal of Thoracic Oncology, Volume 11, Issue 3, March 2016, Pages 312-323

Document Type

Letter to the Editor

Publication Date

10-1-2016

Publication Title

J Thorac Oncol

First Page

128

Last Page

129

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